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The ICD-11 MMS can be viewed online on the WHO's website. In the United States, an expected implementation year of 2025 has been given, but if a clinical modification is determined to be needed (similar to the ICD-10-CM), ICD-11 implementation might not begin until 2027. On 11 February, the WHO claimed that 35 countries were using the ICD-11. The ICD-11 officially came into effect on 1 January 2022. The ICD-11 is distributed under a Creative Commons BY-ND license. MMS stands for Mortality and Morbidity Statistics. The primary derivative of the Foundation is called the ICD-11 MMS, and it is this system that is commonly referred to as simply "the ICD-11". For example, the ICD-O is a derivative classification optimized for use in oncology.

The Foundation is the common core from which all classifications are derived. The WHO-FIC contains the Foundation Component, which comprises all entities of all classifications endorsed by the WHO. The ICD-11 is part of the WHO-FIC, a family of medical classifications. There are also classes for reasons for contact with health services, social circumstances of the patient, and external causes of injury or death.

It usually represents a disease or a pathogen, but it can also be an isolated symptom or (developmental) anomaly of the body. An entity can be anything that is relevant to health care. The ICD-11 is a large taxonomy consisting of about 85,000 entities, also called classes or nodes. Following an alpha version in May 2011 and a beta draft in May 2012, a stable version of the ICD-11 was released on 18 June 2018, and officially endorsed by all WHO members during the 72nd World Health Assembly on. Development of the ICD-11 started in 2007 and spanned over a decade of work, involving over 300 specialists from 55 countries divided into 30 work groups, with an additional 10,000 proposals from people all over the world.

The ICD is developed and annually updated by the World Health Organization (WHO). It replaces the ICD-10 as the global standard for recording health information and causes of death. The ICD-11 is the eleventh revision of the International Classification of Diseases (ICD).